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New book: Optimizing NMR Methods for Structure Elucidation (Oct 18/18)

Optimizing NMR Methods for Structure Elucidation

Optimizing NMR Methods for Structure Elucidation

Authors: Darcy C. Burns and William F. Reynolds (University of Toronto)
Hardcover: 238 pages
Publisher: Royal Society of Chemistry; Sept 2018
Language: English
ISBN: 978-1782625391

This book is aimed at informing organic chemists and natural products chemists on the use of NMR for structure elucidation to enable them to ensure they yield the most reliable possible data in the minimum possible time. It covers the latest pulse sequences, acquisition and processing methods, practical areas not covered in most texts e.g. detailed consideration of the relative advantages and disadvantages of different pulse sequences, choosing acquisition and processing parameters to get the best possible data in the least possible time, pitfalls to avoid and how to minimize the risks of getting wrong structures. Useful in industrial, pharma or research environments, this reference book is for anyone involved with organic chemistry research and, in particular, natural products research requiring advice for getting the best results from the NMR facilities.

Table of contents:

Characterization of Metal–Organic Frameworks

Cover article in Accounts of Chemical Research (Feb 20/18)

Bryan E.G. Lucier, Shoushun Chen, Yining Huang "Characterization of Metal–Organic Frameworks: Unlocking the Potential of Solid-State NMR," Accounts of Chemical Research 51 (2018) 319–330. (Cover Article) http://dx.doi.org/10.1021/acs.accounts.7b00357

February 20, 2018, Volume 51, Issue 2

About the Cover: The local structures, specific molecular-level features, and guest behaviors underpinning desirable properties and applications of metal–organic frameworks are often poorly understood or unknown. Solid-state nuclear magnetic resonance is a powerful tool for MOF characterization that can be used to interrogate the metal center, target linker molecules, and probe guest locations and dynamics.

This article features results obtained using the 21.1 T solid-900state NMR spectrometer at the National Ultrahigh-Field NMR Facility for Solids (Ottawa, ON). If you are interested in using this spectrometer in your research please contact the Facility manager.

Canadian event5th U.S.-Canada Winter School on Biomolecular Solid-State NMR, Stowe, Vermont, USA, January 7-12, 2018 (Oct 11/17)

Tatyana Polenova (U. Delaware), Christopher Jaroniec (Ohio State U.), Mei Hong (MIT) and Bob Griffin (MIT)

Dear Colleagues,

We invite you to encourage your students, postdocs, and senior associates to attend the 5th Winter School on Biomolecular Solid-State NMR, which will be held on January 7-12, 2018, in Stowe, Vermont. Similar to the previous four highly successful Winter Schools, this pedagogical meeting is aimed at students and postdocs in solid-state NMR as well as more senior scientists in related fields who are interested in entering this vibrant field. Our goals are to provide a focused week of teaching of the core concepts and practices in the increasingly multifaceted and complex field of biological solid-state NMR spectroscopy, and to encourage information sharing among different laboratories. Topics to be covered in the 5th Winter School include:

- Basics of solid-state NMR: orientation-dependent NMR frequencies, MAS, tensors and rotations, density operator and its time evolution, decoupling and recoupling techniques, and average Hamiltonian theory
- Multidimensional correlation spectroscopy, non-uniform sampling, techniques for resonance assignment and measurement of structural restraints in biomolecules
- Paramagnetic solid-state NMR techniques
- Techniques for enhancing sensitivity of solid-state NMR: dynamic nuclear polarization and 1H detection
- Solid-state NMR techniques for measuring molecular motion
- Solid-state NMR techniques for structural studies of oriented membrane proteins
- Protein structure calculations in XPLOR-NIH
- Beyond spin 1/2: NMR of quadrupolar nuclei
- Basics of NMR probe design

In addition to lectures, problem sets and their discussion sessions will be given at the meeting.

Speakers: The following have agreed to serve as lecturers: Tim Cross (Florida State), Philip Grandinetti (Ohio State), Bob Griffin (MIT), Mei Hong (MIT), Christopher Jaroniec (Ohio State), Francesca Marassi (Burnham), Ann McDermott (Columbia), Stanley Opella (UC San Diego), Guido Pintacuda (ENS Lyon), Tatyana Polenova (Delaware), Bernd Reif (Tech Univ Munich), Charles Schwieters (NIH), Robert Tycko (NIH), Kurt Zilm (Yale)

Venue and transportation: The meeting will be held at the beautiful and historical Trapp Family Lodge http://www.trappfamily.com/ in Stowe, Vermont. Stowe is accessible from airports in Burlington, VT, Manchester, NH, and Boston, MA. A block of rooms has been reserved at the lodge. We anticipate space for ~70 attendees.

Cost: Room and board will be free for attendees. The registration fee is $500 for academic attendees and $750 for industrial attendees.

Application: Interested students and postdocs should send the following application materials as a single PDF file to:
[ASC-WinterSchool2018 "at" osu.edu]

The application materials include: (1) a CV, (2) publication list, and (3) a 1-page description of your current research and your statement of interest in attending the Winter School. Please indicate your gender in the CV for the purpose of hotel room assignment. Please name this application file as AdvisorLastName_YourLastName_WS2018app.pdf. For example “McDermott_ Smith_WS2018app.pdf”.

Application deadline: Friday, November 3, 2017. Given the limited number of available spaces, it may not be possible to accommodate applications received after this date.

Please distribute this announcement to members of your research group as well as to colleagues who may be interested in attending or sending their group members.

With kind regards,

Tatyana, Chris, Mei & Bob

10th Annual GRASP Symposium, Nov 20, 2017, McGill University, Montréal, QC (Oct 8/17)

Canadian event10th Annual GRASP Symposium
November 20, 2017, McGill University, Montréal, QC, Canada

Dear colleagues,

You are invited to attend the 10th Annual GRASP Symposium to be held on Monday, November 20th, 2017

The deadline for online registration is Sunday November 5, 2017. Registration is required for all attendees at

Please feel free to contact me at grasp.med "at" mcgill.ca if you have any question.

Best regards,


QANUC Grand Reopening and EPR Symposium and Workshop, McGill University, Montreal, July 21, 2017 (June 15/17)


To celebrate the re-opening of QANUC (Quebec / Eastern Canada High-Field NMR Facility) with the installation of the new 800 MHz NMR instrument and the addition of EPR to the McGill Chemistry Magnetic Resonance Facility, we are holding a symposium on Friday July 21st.

In the morning, NMR talks will start off with an opening lecture by Prof. Christian Griesinger (MPI Gottingen) and include talks from local users Kathy Borden, Nick Doucet, Pascale Legault and the QANUC Director, Anthony Mittermaier. In parallel, an EPR workshop run by Bruker will take place in the EPR lab.

Lunch and lab tours will be followed by EPR talks featuring John McCracken (Michigan State University), Gunnar Jeschke (ETH Zurich), Sushil Misra (Concordia), and Scott Bohle (McGill). The theme is “What EPR Can Do For You” and anyone interested in EPR is welcome! Also in the afternoon, Tara Sprules will lead a workshop on multi-dimensional data processing using NMRPipe (geared towards grad students/postdocs that are actively working on an NMR project).


Visit the website for more information and to sign up (required). Contact Robin Stein for information about the EPR workshop and talks and Tara Sprules for information about the NMR workshop and talks, and please forward this to anyone who might be interested.

Robin Stein and Tara Sprules

Robin Stein
NMR/EPR Facility Manager

Dept of Chemistry, McGill University
Room 35B, Otto Maass, 801 Sherbrooke St. West
Montreal, QC H3A 0B8

Web: http://nmr.chem.mcgill.ca
Twitter: https://twitter.com/mcgillnmr

First Mid-Canada NMR Symposium and the 28th Annual Mid-Canada AOAC Day, June 21, 2017, Winnipeg, MB (May 23/17)

Wednesday, June 21, 2017, Victoria Inn Hotel and Convention Centre, Winnipeg, Manitoba

NMR Workshop, presented by Bruker Canada
Nicole Kruse (Bruker) What can NMR do for the chemist? Introduction to experiments beyond 1D proton and carbon spectra

Topics will include
- 2D experiments commonly used for structure verification
- Examination of NMR active nuclei for inorganic chemist

- Introduction to Magic Angle Spinning (HR-MAS and MAS) methods
- Triple resonance bio-molecular NMR

Keynote Speaker
Sonya Havens (IISD Experimental Lakes) The Experimental Lakes Area: Whole ecosystem aquatic research since 1968

Invited Speakers
- Richard Shoemaker (Bruker) What’s New with Bruker in 2017 ?
- Scott Kroeker (University of Manitoba) Expanding the NMR palette: multinuclear magnetic resonance of glasses, coordination polymers and paramagnetic solids
- Melanie Martin (University of Winnipeg) Measuring the Microscopic Using Magnetic Resonance Imaging

Who should attend
Scientists, Industry, NMR managers & NMR Facility Technologists, Post-doctoral Fellows and Graduate Students

Registration fee: $30 (including lunch), free registration for students

To register: http://midcanadaaoac.com/home/

11th VIVA NMR symposium, St. John's College, The University of British Columbia, July 21st, 2017 (May 20/17)

I am very pleased to announce the 11th VIVA NMR symposium is to be held at St. John's College, The University of British Columbia on July 21st, 2017.

VIVA NMR symposium is an annual NMR mini-symposium that is intended to foster a community among Pacific Northwest researchers using Nuclear Magnetic Resonance (NMR) spectroscopy. The idea is to provide a venue for student researchers to have the opportunity to give oral and poster presentations in a small welcoming environment, locally so it is affordable. We welcome presentations that are related to any sub-areas of NMR including, but not limited to, theoretical, method development or simply applications in your current research projects.

Registrations and details can be found on the following website:


Detailed programs will be furnished after the expiry date of the registration.

I look forward to welcoming you to VIVA NMR symposium.

Zhicheng Xia, Ph.D.
Director of The NMR Facilities
Department of Chemistry
University of British Columbia

New book: Essential Mathematics for NMR and MRI Spectroscopists (Jan 5/17)

Essential Mathematics for NMR and MRI Spectroscopists

Essential Mathematics for NMR and MRI Spectroscopists

by Keith C. Brown (University of Saskatchewan)
Hardcover: 551 pages
Publisher: Royal Society of Chemistry; Feb 2017
Language: English
ISBN: 978-1782627975

RSC: Beginning with a review of the important areas of mathematics, this book then covers many of the underlying theoretical and practical aspects of NMR and MRI spectroscopy from a maths point of view. Competence in algebra and introductory calculus is needed but all other maths concepts are covered. It will bridge a gap between high level and introductory titles used in NMR or MRI spectroscopy. Uniquely, it takes a very careful and pedagogical approach to the mathematics behind NMR and MRI. It leaves out very few steps, which distinguishes it from other books in the field.

The author is an NMR laboratory manager and is sympathetic to the frustrations of trying to understand where some of the fundamental equations come from hence his desire to either explicitly derive all equations for the reader or direct them to derivations. This is an essential text aimed at graduate students who are beginning their careers in NMR or MRI spectroscopy and laboratory managers if they need an understanding of the theoretical foundations of the technique.

Table of contents:

Dr. Lewis Kay appointed to Order of Canada (Jan 4/17)

via SickKids

January 4, 2017

SickKids’ Dr. Lewis Kay appointed to Order of Canada

Dr. Lewis Kay, Senior Scientist at The Hospital for Sick Children (SickKids) and a Professor in the Departments of Molecular Genetics, Chemistry and Biochemistry at the University of Toronto, was named an Officer of the Order for Canada, one of the country’s most prestigious civilian honours. The announcement was made December 30, 2016.

The Order of Canada recognizes a lifetime of achievement. Kay is being cited for his pioneering research in biochemistry and medical imaging science, which explores the structure and behaviour of proteins.

“I am thrilled to congratulate Dr. Kay on this well-deserved honour. His development and application of new NMR methods that link protein dynamics to biological function have made and continue to make an extraordinary contribution to our country and our world,” says Dr. Michael Salter, Chief of Research, SickKids.

Kay is a researcher in Molecular Structure & Function at the SickKids Research Institute. His laboratory focuses on the development of nuclear magnetic resonance (NMR) techniques for studying macromolecular structure and dynamics, and the application of NMR techniques to problems of biological and clinical importance. He has extended NMR from a technique used to probe small protein systems to one that enables the study of molecular machines at atomic resolution and has used these techniques to demonstrate the importance of dynamics in such critical components of the cell. He is also a Canada Research Chair in Proteomics, Bioinformatics and Functional Genomics.

Nearly 7,000 people from all sectors of society have been invested into the Order since it was established in 1967. Kay will receive his insignia at a ceremony at a later date. Learn more on the Order of Canada website.

CSC 2017 100th Canadian Chemistry Conference and Exhibition (Dec 12/16)

From Rui Resendes,
President, Canadian Society for Chemistry

Dear CSC members,

I invite you to attend the 100th Canadian Chemistry Conference and Exhibition (CSC 2017) next May 28-June 1, 2017 in Toronto. The Canadian Society for Chemistry (CSC) is working with the University of Toronto Chemistry Department to plan this centenary event under the theme "A Celebration of Chemistry." I invite you to submit your abstract for this milestone conference and encourage you to promote this event to your colleagues, both in Canada and internationally.

CSC 2017 will be the largest national event for chemical scientists working in academia, industry or government.

Conference Features:
•World renowned plenary lecturers: Charles Lieber and Sir Martyn Poliakoff
•Jointly organized international symposia
•Industrial program
•Professional development program, and poster sessions.
•Outreach event led by Molly Shoichet.
•Largest ever CSC conference Exhibition Hall

I would like to thank the University of Toronto organizing committee: Conference Chair Robert Batey, Technical Program Chair Mark Lautens, and Sponsorship Chair Doug Stephan for their tireless efforts in planning CSC's centenary conference.

Please visit the CSC 2017 website frequently as details will be posted regularly throughout the coming months.

I look forward to seeing you in Toronto!

Best regards,

Rui Resendes
President, Canadian Society for Chemistry

Abstract submission and registration is now open

Consider attending two NMR-related symposia:

"Advances in Solid State NMR: Inorganic Materials, Biological Solids and Theoretical Methods" http://www.csc2017.ca/node/254

Robert Schurko, University of Windsor
Simon Sharpe, The Hospital for Sick Children

"Protein Machines and Allostery"

Lewis Kay , University of Toronto
Giuseppe Melacini, McMaster University
Scott Prosser, University of Toronto

Invited Speakers:
Andy Byrd, National Cancer Institute
Nick Doucet, INRS-Institut Armand-Frappier Research Centre
James Fraser, University of California - San Francisco, USA
Lewis Kay, University of Toronto
Julie Kitevski, University of Toronto
Giuseppe Melacini, McMaster University
Anthony Mittermaier, McGill University
Scott Prosser, University of Toronto
Filip Van Petegem, University of British Columbia
Gianluigi Veglia, University of Minnesota, USA
Derek Wilson, York University

ISMAR 2017 Abstract Submission and Registration
now open
(Dec 1/16)

Québec City, July 23-28, 2017900

Join us in Québec City, Canada for ISMAR 2017, the 20th Meeting of the International Society of Magnetic Resonance, held jointly with the Rocky Mountain Conference on EPR

Dear Colleagues,

On behalf of the Organizing Committee we would like to invite you to participate in ISMAR 2017 to be held in Québec City, Canada, 23 - 28 July 2017. This meeting will be held jointly with the Rocky Mountain Conference on EPR. As the birthplace of French North America, Québec’s capital is an open-air treasure trove sure to delight history buffs. Old Québec has been attracting travellers for generations. The historic walled city exudes Old-World charm, with its narrow, winding streets and extensive array of boutiques, museums, and attractions.

ISMAR 2017, like preceding ISMAR conferences, is a top level international conference bringing together scientists from around the world interested in recent developments in magnetic resonance. The primary goal of ISMAR 2017 is to present state-of-the-art research, recent achievements and global trends in magnetic resonance and to promote cross disciplinary interactions that can spur the development of this exciting research field.

ISMAR 2017 will also be a primary showcase for novel technologies, instrumentation and applications touching every aspect of magnetic resonance.

Topics for the conference will include:
• Solution NMR
• Solid-State NMR Materials/Methods
• Solid-State NMR Biological Applications/Methods
• MRI Methods, Medicine, Materials
• Hyperpolarization
• In vivo/In-cell
• Unusual
• EPR, biological
• EPR, materials
• EPR, methods, theory
• EPR, medicine

Confirmed Plenary Speakers are:
• Hanudatta S. Atreya, Indian Institute of Science, India
• Enrica Bordignon, Rurh Universität Bochum, Germany
• Jiangfeng Du, University of Science and Technology of China, China
• Song-I Han, University of California Santa Barbara, USA
• Lewis E. Kay, University of Toronto, Canada
• Malcolm H. Levitt, University of Southampton, UK
• Tatyana Polenova, University of Delaware, USA
• Klaus Schmidt-Rohr, Brandeis University, USA
• Christina Thiele, Technische Universität Darmstadt, Germany
• Robert Tycko, National Institutes of Health, USA

We look forward to welcoming you to ISMAR 2017.

Michèle Auger and Isabelle Marcotte, Chairs
David Bryce, Co-Chair

To submit your abstract

To register

Please visit the conference website for updates

And follow ISMAR2017 on social media