Gang Wu (Department of Chemistry)
Françoise Sauriol (NMR Facility)
Steven Smith (Department of Biomedical and Molecular Sciences/PFD)
Protein Function Discovery (PFD) Research and Training Program
|C&EN: Nitroprusside Color Mystery Resolved (Oct 26/15)|
|Y. Gao, A. Toubaei, X. Kong, G. Wu, "Solving the 170-Year-Old Mystery About Red-Violet and Blue Transient Intermediates in the Gmelin Reaction," Chemistry - A European Journal 21 (2015) 1717217177. (Feature Article) http://dx.doi.org/10.1002/chem.201503353|
|Chemical & Engineering News Concentrates "Nitroprusside Color Mystery Resolved" Volume 93 (2015), Issue 42, page 23. http://cen.acs.org/articles/93/i42/Nitroprusside-Color-Mystery-Resolved.html|
"Canadian NMR Research"
News Bulletin (Nov 18/13)
Thanks for reading!
Colleagues, the Spring 2013 issue of the "Canadian NMR Research" news bulletin is ready for your attention, our traditional mix of news and research updates. In this issue: DNP-NMR at Guelph, 850 MHz at McMaster, and the first MOOT XXVI announcement. You are welcome to share this bulletin with your colleagues and students.
|Gang Wu, Zhehong Gan, Irene C. M. Kwan, James C. Fettinger, and Jeffery T. Davis, "High Resolution 39K NMR Spectroscopy of Bio-organic Solids," J. Am. Chem. Soc. 133 (2011) 1957019573. (cover article) http://dx.doi.org/10.1021/ja2052446|
"Oxygen 17 NMR Studies of Organic and Biological Molecules",
Encyclopedia of Magnetic Resonance (2011). http://dx.doi.org/10.1002/9780470034590.emrstm1212
D.I. Hoult "Magnetic Resonance with Conducting and High- Dielectric Samples", Encyclopedia of Magnetic Resonance (2011). http://dx.doi.org/10.1002/9780470034590.emrstm1182
Cambridge Isotope Laboratories (CIL) made available a series of application notes on the use of stable isotopes in Biomolecular NMR. These application notes were written by some of the world's leading researches in the field, including several Canadian scientists.
Lewis Kay (University of Toronto) "Alanine Probes of Supra-Molecular Structure and Dynamics", page 9.
Leonid S. Brown and Vladimir Ladizhansky (University of Guelph) "Pichia pastoris as a Eukaryotic Protein Isotope-Labeling System", pages 14-15.
Ying Fan, Lichi Shi, Vladimir Ladizhansky and Leonid S. Brown (University of Guelph) "Uniform Isotope Labeling of Eukaryotic Proteins in Methylotrophic Yeast for High-Resolution NMR Studies - Extension to Membrane Proteins", Application Note 26, pages 71-74.
Recent research by Gang Wu's group (Queen's University) is cited as an example of advanced 17O NMR spectroscopy in large protein-ligand complexes in solution and in the solid state, "17O NMR reagents", page 34.
application notes are available for download as a PDF file (5.1MB) "Stable
Isotopes for Structural Biomolecular NMR Catalog" at:
|Gang Wu and Jianfeng Zhu "NMR studies of alkali metal ions in organic and biological solids," Progress in Nuclear Magnetic Resonance Spectroscopy (2011) accepted. (Invited Review) http://dx.doi.org/10.1016/j.pnmrs.2011.06.002|
the Canadian Chemical News, March, 2011
Latest News: New NMR Technique Solves Oxygen Puzzle (online)
(print, ACCN, Volume 63, Number 3, p. 9)
Low concentration and poor sensitivity often hinder or make impossible solid-state 17O NMR in large biomolecular systems. In this cover article in Angewandte Chemie Gang Wu (Queens) and co-workers from the University of Ottawa and NRC Canada show that at an ultrahigh magnetic field of 21 T the high quality solid-state 17O NMR spectra can be obtained for large proteinligand complexes of up to 300 kDa in size. Complementary multinuclear 17O, 27Al, and 13C NMR data obtained in this work have aided in the structural refinement for an ovotransferrin bound Al-oxalate complex.
Jianfeng Zhu, Eric Ye, Victor Terskikh, and Gang Wu, "Solid-State 17O NMR Spectroscopy of Large Protein-Ligand Complexes," Angewandte Chemie International Edition 49 (2010) 8399-8402. (Cover Article) http://dx.doi.org/10.1002/anie.201002041
November 18, 2010
Molecular Oxygen Studies Targeted by New Tool
University News Center, November 17, 2010
Scientists discover new method for studying molecules
This is an ninth cover article featuring results obtained using resources of the National Ultrahigh-Field NMR Facility for Solids. See our cover gallery and the complete list of research publications enabled by the Facility here (complete list).
National Ultrahigh-Field NMR Facility for Solids wishes to extend its sincere
thanks to Yining Huang (Western), the outgoing member of the Facility
Steering Committee who served in 2006-2010. Yining has done a great job as
the representative for Ontario Universities. His valuable insights and suggestions
have certainly helped to improve the Facility and broaden its userbase.
The Facility is pleased to announce that Gang Wu (Queen's) has been appointed to serve on the Facility Steering Committee as the representative for Ontario Universities for the next three years. Gang Wu is a long-time facility user and his first-hand experience will be very useful in managing the Facility. Welcome aboard, Gang!
To contact members of the Facility Steering Committee
The front page of the Summer 2009 issue of the "Canadian NMR Research" news bulletin features a news report about a special NMR symposium in honour of Professor Rod Wasylishen which was held during the 55th International Conference on Analytical Sciences and Spectroscopy (ICASS) at Queens University on August 9-12, 2009. The symposium was organized by Gang Wu and was attended by more then 50 of Rod's colleagues and friends. Read more here.
This high-profile special issue of PCCP guest-edited by Paul Hodgkinson (Durham, UK) and Stephen Wimperis (Glasgow, UK) will be presented to the participants of the upcoming 6th Alpine Conference on Solid-State NMR in September 2009 (conference web-site). Among many excellent reviews and research papers highlighting recent trends and progress in the field of solid-state NMR spectroscopy there are four by Canadian researchers, including the front cover article by Gang Wu's group from Queen's.
Pedro M. Aguiar, Michael J. Katz, Daniel B. Leznoff and Scott Kroeker, "Natural abundance 13C and 15N solid-state NMR analysis of paramagnetic transition-metal cyanide coordination polymers," Physical Chemistry Chemical Physics 11 (2009) 6925-6934. (Invited Article, Themed Issue) http://dx.doi.org/10.1039/b907747b
Jianfeng Zhu, Amanda J. Geris and Gang Wu, "Solid-state 17O NMR as a sensitive probe of keto and gem-diol forms of alpha-keto acid derivatives," Physical Chemistry Chemical Physics 11 (2009) 6972-6980. (Cover Article, Themed Issue) http://dx.doi.org/10.1039/b906438a
Rebecca P. Chapman and David L. Bryce, "Application of Multinuclear Magnetic Resonance and Gauge-Including Projector-Augmented Wave Calculations to the Study of Solid Group 13 Chlorides," Physical Chemistry Chemical Physics 11 (2009) 6987-6998. (Invited Article, Themed Issue) http://dx.doi.org/10.1039/b906627f
Luke A. O'Dell and Robert W. Schurko, "Static solid-state 14N NMR and computational studies of nitrogen EFG tensors in some crystalline amino acids," Physical Chemistry Chemical Physics 11 (2009) 7069-7077. (Invited Article, Themed Issue) http://dx.doi.org/10.1039/b906114b
The 55th International Conference on Analytical Sciences and Spectroscopy (ICASS) will be held at Queens University (Kingston, Ontario, Canada) on August 9-12, 2009. The conference will feature a special NMR Symposium in honour of Professor Rod Wasylishen.
The conference will also have a fantastic social program including the Magical Dinner with Canada's Magic Champion Eric Leclerc and a very popular Sunset Dinner Cruise of the Thousand Islands.
The abstract submission for oral and poster presentations is now open and will last until June 1, 2009.
ICASS offers a special discount for early bird registration which is available until April 1, 2009.
Please check the ICASS conference website for details: http://www.icass.ca/2009/
contact the NMR Symposium organizer, Gang Wu, for more information
Recent JACS Communication by Gang Wu and Irene Kwan (Wu's group, Queen's University) is highlighted as News of the week in Chemical & Engineering News as an important contribution to our understanding of self-assembly of nucleotide monomers. In their research Gang and Irene have used a variety of liquid-state NMR techniques and computations to characterize guanosine 5'-monophosphate (5'-GMP) solutions in the presence of sodium cations. The authors have observed spontaneous formation of well-defined right-handed helical 5'-GMP structures, the finding which may have potential implications for prebiotic chemistry theories.
the news story in C&EN (picture credit)
Issue February 16, 2009, p.10, News of the week:
G. Wu and I. Kwan, "The helical structure of disodium guanosine 5-monophosphate self-assembly in neutral solution," Journal of the American Chemical Society 131 (2009) 31803182. http://dx.doi.org/10.1021/ja809258y
Join us in congratulating Gang Wu (Queen's University) who has been promoted to the rank of Professor !
Queen's Department of Chemistry Prof. Gang Wu carries out an extensive
research program in Physical and Computational chemistry involving solid-state
NMR. Gang Wu is also a frequent user of the 900 NMR Facility in Ottawa.
Photo from : http://www.chem.queensu.ca
"One of Canada's leading universities with an international reputation for scholarship, research, social purpose, spirit, and diversity, Queen's is also well-known for its incomparable 24-hour learning environment. The Queen's experience combines great teaching, people, and tradition on a campus with a global reputation in the heart of a vibrant community. Queen's is a university that can bring out the best from inside of you."
"Queen's is one of Canada's leading research-intensive universities. Queen's researchers are conducting innovative studies across a broad spectrum of disciplines from the humanities and social sciences to the physical, natural, and applied sciences."