Pedro Aguiar (NMR Chemistry)
James Omichinski (Biochimie)
Michael Osborne (IRIC NMR)
As a structural biology specialist (NMR spectroscopy and X-ray crystallography), you will be responsible for optimal usage of a new structural biology facility at UdeM under the direction of the professor responsible for the facility and in close collaboration with members of the department. Your duties will include user training, equipment operation and maintenance as well as development of experimental protocols associated with research projects and academic training.
Provide user training and oversee instrument usage of all the equipment within the structural biology facility (500 MHz, 600 MHz, and 700 MHz NMR spectrometers, liquid handling robots, stereomicroscopes, crystallisation chambers, light-scattering equipment (MALS/RI), etc)
Assure the optimal operation of equipment and offer technical assistance when needed
Assure the maintenance of the structural biology equipment
Develop and implement protocols for instrument maintenance, data collection and analysis, both in French and English
Contribute to budget planning for the facility and to purchasing consumables and new equipment
Collaborate with departmental staff for planning of instrument schedule, billing, and maintenance of a web page describing the facility
Participate in the development of didactic material for teaching undergraduate and graduate students
Serve as a resource for users, providing expert advice in experiment planning and data analysis
Coordinate with manufacturers for preventive maintenance and repairs
Maintain professional and technical knowledge
Promote the facility
Ensure the safety of users and personnel who have access to the facility
Skills and qualifications
education and experience:
Applicants must have a MSc and three (3) years of relevant experience or PhD degree in Chemistry, Biochemistry or related discipline
Experience in structural biology, especially in NMR spectroscopy and X-ray crystallography
Experience in using computer software and developing computer scripts for structural biology applications
Oral and written communication skills, both in French and English
Experience in instrument maintenance and repair
Demonstrated ability to train students
Other qualifications: autonomy, scientific rigor, sense of organization, capacity for teamwork
Salary scale (hourly) : $27.36 to $39.31
Supervisor: Pascale Legault, Professor, Department of Biochemistry and Molecular Medicine
Location : Roger-Gaudry Building, Université de Montréal, Montreal, Quebec, Canada
Working hours: Monday to Friday, 9h00 to 17h00
Please send a curriculum vitae listing all publications and a list of three references as well as a cover letter to: [ pascale.legault "at" umontreal.ca ]
Département de Biochimie et Médecine Moléculaire
Université de Montréal
E-mail: pascale.legault "at" umontreal.ca
Blaine Chronik (Western) Magnetic Resonance Systems Development
Kalle Gehring (McGill) Protein folding in the endoplasmic reticulum
Paul Hazendonk (Lethbridge) Solid-State NMR of Complex Hybrid Organic-Inorganic Materials
William MacFarlane (UBC) Development and Application of Depth-Resolved beta-Detected Nuclear Magnetic Resonance to electronic, ionic and molecular phenomena in the Solid State
Anthony Mittermaier (McGill) Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
Geoffrey Ozin (Toronto) Silicon Nanochemistry
Linda Reven (McGill) Solid-State NMR of Polymer and Liquid Crystalline Nanocomposites
Andre Simpson (Toronto Scarborough) Development of flow-based and magic angle spinning in-vivo NMR to understand environmental stress
Jenifer Thewalt (Simon Fraser) Domains in Biologically Relevant Lipid Membranes
Julian Zhu (Université de Montréal) Versatile Polymeric Biomaterials
Discovery Accelerator Supplement
$120,000 over three years
|Giuseppe Melacini (McMaster) Solution NMR Studies of Interactions of Ligands With Plasma Proteins|
Research Tools and Instruments (RTI)
|Derek Gates (UBC) Upgrade to UBC-Chemistry Departmental NMR Facility|
N. Goudreau, R. Coulombe, A.-M. Faucher, C. Grand-Maitre, J.-E. Lacoste, C.T. Lemke, E. Malenfant, Y. Bousquet, L. Fader, B. Simoneau, J.-F. Mercier, S. Titolo, and S.W. Mason, "Monitoring Binding of HIV-1 Capsid Assembly Inhibitors Using 19F Ligand-and 15N Protein-Based NMR and X-ray Crystallography: Early Hit Validation of a Benzodiazepine Series," ChemMedChem 8 (2013) 405–414. (Cover Article) http://dx.doi.org/10.1002/cmdc.201200580
Chemistry (RSC) profiles Prof. Julian Zhu (Université
de Montréal) as the author of the week.
H.N. Cheng, T. Asakura, A.D. English
This ACS Symposium Series book includes papers presented at the Symposium "NMR Spectroscopy of Polymers - Innovative NMR Strategies for Complex Macromolecular Systems" which was part of Pacifichem 2010, the 2010 International Chemical Congress of Pacific Basin Societies in Honolulu, Hawaii, December 15-20, 2010. Among over 30 contributions on the state-of-the-art NMR spectroscopy in polymers and related systems there are two chapters by Canadian NMR research groups.
P.M. Macdonald, "Diffusion NMR of Polymers in Bicelles," Chapter 14, NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules, Eds. H.N. Cheng, T. Asakura, A.D. English, ACS (2011) pp. 221-250. http://dx.doi.org/10.1021/bk-2011-1077.ch014
H. Thérien-Aubin, Y.J. Wang, and X.X. Zhu, "NMR Imaging and Its Application in the Study of Pharmaceutical Tablets," Chapter 27, NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules, Eds. H.N. Cheng, T. Asakura, A.D. English, ACS (2011) pp. 441-457. http://dx.doi.org/10.1021/bk-2011-1077.ch027
The 94th Canadian Chemistry Conference and Exhibition (CSC 2011) "Chemistry and Health" will be held in Montréal, Québec from June 5-9, 2011, as a joint effort of the Canadian Society for Chemistry and the four Montréal Universities, with the Université de Montréal Chemistry Department as the host. The CSC is the largest annual national event for chemical professionals attracting close to 2500 participants each year.
Canada is very dynamic in Nuclear Magnetic Resonance spectroscopy and to pursue the tradition, a solid-state NMR workshop as well as two 1.5-day NMR symposia are scheduled to cover a wide range of applications and developments in the fields of solution and solid-state NMR.
Profs Anthony Mittermaier (McGill University) and Pierre Lavigne (Université de Sherbrooke) are organizing the "Solution NMR: Biomolecular structure, dynamics, and function" symposium which includes, amongst a list of over 15 speakers, Charalampos Kalodimos (Rutgers U.). Brian Sykes (U. of Alberta), Gary Shaw (U. Western Ontario) and Lawrence McIntosh (UBC).
Profs Michel Lafleur (Université de Montréal) and Isabelle Marcotte (Université du Québec à Montréal) are co-organizers of the symposium entitled "Solid-state NMR: From materials to biomolecules". So far, Profs Marc Baldus (U. of Utrecht), Vladimir Ladizhansky (U. of Guelph), Bruce Balcom (U. New Brunswick), Valerie Booth (Memorial U.) and Dr. Ansgar Siemer (Columbia U.) have confirmed their presence as guest speakers.
invite you to participate in the CSC2011 conference which plenary lecturer
will be Nobel Laureate Prof. Roger Tsien (U. of California, San Diego).
More detail on the symposia, abstract submission and registration can be
found on the conference website at http://www.csc2011.ca
The deadline for abstract submission is February 15, 2011.
Submit your abstract through Hermes Conference Centre via the CSC2011 website. Details are available at http://www.csc2011.ca/Program/submit_abstract.html
NMR Symposia Organizers